A Basket Trial is a type of clinical trial methodology that allows researchers to evaluate the effectiveness of a new drug or treatment across multiple diseases or conditions that share common genetic mutations or molecular characteristics. Unlike traditional clinical trials that focus on a single disease, basket trials group patients by these genetic or molecular markers rather than by the type of cancer or disease they have. This approach enables a more targeted and efficient process for testing potential treatments.
Basket trials play a crucial role in advancing personalized medicine by offering a streamlined and innovative approach to drug development and clinical research. By focusing on genetics and molecular markers, basket trials can accelerate the drug approval process, reduce costs, and lead to more effective and tailored treatments for patients.